VMware vSphere / Physical: App-consistent snapshots can be taken every 1 to 12 hours. Snapshots are standard Azure blob snapshots. The Mobility agent running on a VM requests a VSS snapshot in accordance with this setting, and bookmarks that point-in-time as an application consistent point in the replication stream.

Hyper-V: App-consistent snapshots can be taken every 1 to 12 hours. Dynamic disks are not supported for app-consistent snapshots

Azure IaaS: An App-consistent snapshots can be created every 60 minutes.

Microsofts Volume Shadow Copy Service (VSS) is leveraged for achieving application consistency. VSS operates at the block-level. The aim of VSS is to create consistent reliable snapshots by temporarily halting new writes and letting ongoing writes finish. Microsoft applications that support VSS are Active Directory, MSSQL, Exchange and SharePoint. VSS is also leveraged to create file system consistent snapshots of Microsoft NTFS volumes.