HX220c M5 and HXAF220c M5 1U appliances have 8 SFF disk slots.

HX220x M5 Edge (hybrid/all-flash) are the only systems that support less than 6 drives (3-6).

HX 3.5 adds support for Intel Optane NVMe DC SSDs and Cisco HyperFlex All-NVMe appliances. All-NVMe appliances leverage the ultra-fast Intel Optane NVMe drives for caching and Intel 3D NAND NVMe drives for capacity storage.

HX220c M5 (hybrid):
1 x 240GB SATA M.2 SSD for boot
1 x 240GB SATA SSD for system
1 x 480GB SATA SSD, 800GB SAS SSD or 800GB SAS SED SSD for caching
6-8 x 1.2TB/1.8TB/2.4TB SAS 10K HDD or 1.2TB SAS 10k SED HDD for data.

HXAF220c M5 (all-flash):
1 x 240GB SATA M.2 SSD for boot
1 x 240GB SATA SSD for system/log
1 x 375GB Optane/400GB/1.6TB SAS SSD, 1.6TB NVMe SSD or 800GB SAS SED SSD for caching
6-8 x 960GB/3.8TB SATA SSD or 800GB SAS/960GB SATA/3.8TB SATA SED SSD for data

HXAN220c M5 (all-NVMe):
1 x 240GB SATA M.2 SSD for boot
1 x 375GB NVMe for system/log
1 x 1.6TB NVMe SSD for caching
6-8 x 1.0TB/4.0TB NVMe SSD for data


HX240c M5 and HXAF240c M5 2U appliances have 24 front-mounted SFF disk slots and 1 internal SFF disk slot. The storage configuration is flexible.

HX240c M5 SFF (hybrid):
1 x 240GB SATA M.2 SSD for boot
1 x 240GB SATA SSD for system
1 x 1.6TB SAS/SATA SSD or 1.6TB SAS SED SSD for caching
6-23 x 1.2TB/1.8TB/2.4TB SAS 10K HDD or 1.2TB SAS 10k SED HDD for data

HX240c M5 LFF (hybrid):
1 x 240GB SATA M.2 SSD for boot
1 x 240GB SATA SSD for system
1 x 3.2TB SATA SSD for caching
6-12 x 6.0TB/8.0TB/12TB SATA 7.2K HDD

HXAF240c M5 (all-flash):
1 x 240GB SATA M.2 SSD for boot
1 x 240GB SATA SSD for system/log
1 x 375GB Optane/400GB/1.6TB SAS SSD, 1.6TB NVMe SSD or 800GB SAS SED SSD for caching
6-23 x 960GB/3.8TB SATA SSD or 800GB SAS/960GB SATA/3.8TB SATA SED SSD for data


AF = All-Flash
AN = All-NVMe
SED = Self-Encrypting Drive
SFF = Small Form Factor