Single-Layer: HPE SimpliVity 380 is meant to be used as a storage platform as well as a compute platform at the same time. This effectively means that applications, hypervisor and storage software are all running on top of the same server hardware (=single infrastructure layer).
Although HPE SimpliVity 380 can serve in a dual-layer model by providing storage to non-HPE SimpliVity 380 hypervisor hosts, this would negate many of the platforms benefits as well as the financial business case. (Please view the compute-only scale-out option for more information).